NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1131341
rs1131341 		0.925 0.160 16 69714966 missense variant G/A;C snv 3.2E-02 2.6E-02
CUI: C0685938
Disease: Malignant neoplasm of gastrointestinal tract
Malignant neoplasm of gastrointestinal tract 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2014 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		Neoplasms 0.010 < 0.001 1 2006 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2003 2003
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		Neoplasms 0.010 < 0.001 1 2006 2006
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2003 2003
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0685938
Disease: Malignant neoplasm of gastrointestinal tract
Malignant neoplasm of gastrointestinal tract 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C4082937
Disease: Necrotizing enterocolitis in fetus OR newborn
Necrotizing enterocolitis in fetus OR newborn 		Digestive System Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.020 0.500 2 2002 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		Immune System Diseases; Nervous System Diseases 0.020 0.500 2 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.020 0.500 2 2012 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.020 0.500 2 2002 2006
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 0.500 2 2012 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.060 0.667 6 2006 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.070 0.714 7 2006 2019
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.040 0.750 4 2006 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.040 0.750 4 2006 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.040 0.750 4 2004 2017
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.040 0.750 4 2004 2017
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.040 0.750 4 2004 2017
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.060 0.833 6 2004 2016