NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 1.000 1 1999 1999
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 1999 1999
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.010 1.000 1 1999 1999
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.010 1.000 1 1999 1999
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2003 2003
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2003 2003
dbSNP: rs1131341
rs1131341 		0.925 0.160 16 69714966 missense variant G/A;C snv 3.2E-02 2.6E-02
CUI: C4054727
Disease: Infant Acute Lymphoblastic Leukemia
Infant Acute Lymphoblastic Leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2005 2005
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C4054727
Disease: Infant Acute Lymphoblastic Leukemia
Infant Acute Lymphoblastic Leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2005 2005
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C4054727
Disease: Infant Acute Lymphoblastic Leukemia
Infant Acute Lymphoblastic Leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2005 2005
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.020 0.500 2 2002 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2004 2006
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.020 0.500 2 2002 2006
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		Neoplasms 0.010 < 0.001 1 2006 2006
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		Neoplasms 0.010 < 0.001 1 2006 2006
dbSNP: rs1020475809
rs1020475809 		0.925 0.080 16 69711027 synonymous variant A/G snv 2.0E-05 7.0E-06
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1020475809
rs1020475809 		0.925 0.080 16 69711027 synonymous variant A/G snv 2.0E-05 7.0E-06
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0008626
Disease: Congenital chromosomal disease
Congenital chromosomal disease 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities 0.010 1.000 1 2008 2008
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.020 1.000 2 2003 2009
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.020 1.000 2 2003 2009
dbSNP: rs1182593032
rs1182593032 		0.851 0.200 16 69718516 missense variant A/G snv
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		Digestive System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C3714760
Disease: Drug-induced tardive dyskinesia
Drug-induced tardive dyskinesia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders 0.030 1.000 3 2006 2010