PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		Pathological Conditions, Signs and Symptoms 0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C3149706
Disease: CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO
CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		Pathological Conditions, Signs and Symptoms 0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C2674665
Disease: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding)
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding) 		0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 < 0.001 1 2002 2002
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		Eye Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0042373
Disease: Vascular Diseases
Vascular Diseases 		Cardiovascular Diseases 0.010 1.000 1 2002 2002
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs13306698
rs13306698 		0.882 0.240 7 95311470 missense variant T/C snv 6.0E-03 1.9E-03
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2003 2003
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2003 2003
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1843013
Disease: Alzheimer disease, familial, type 3
Alzheimer disease, familial, type 3 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2003 2003
dbSNP: rs72552787
rs72552787 		0.925 0.080 7 95315388 missense variant T/C snv
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2003 2003
dbSNP: rs72552787
rs72552787 		0.925 0.080 7 95315388 missense variant T/C snv
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2003 2003
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		Nervous System Diseases; Cardiovascular Diseases 0.020 0.500 2 2001 2004
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		Cardiovascular Diseases 0.010 1.000 1 2004 2004
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		Eye Diseases 0.010 1.000 1 2004 2004
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0039585
Disease: Androgen-Insensitivity Syndrome
Androgen-Insensitivity Syndrome 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases 0.010 1.000 1 2004 2004
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0155017
Disease: Color Blindness, Blue
Color Blindness, Blue 		Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases 0.010 < 0.001 1 2005 2005
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		Mental Disorders 0.010 1.000 1 2005 2005
dbSNP: rs755603793
rs755603793 		0.925 0.080 7 95308077 missense variant C/T snv 1.6E-05
CUI: C0206064
Disease: Microvascular Angina
Microvascular Angina 		Cardiovascular Diseases 0.010 1.000 1 2005 2005
dbSNP: rs755603793
rs755603793 		0.925 0.080 7 95308077 missense variant C/T snv 1.6E-05
CUI: C0002963
Disease: Angina Pectoris, Variant
Angina Pectoris, Variant 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2005 2005
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		Mental Disorders 0.010 1.000 1 2005 2005