PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		Pathological Conditions, Signs and Symptoms 0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C3149706
Disease: CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO
CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		Pathological Conditions, Signs and Symptoms 0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C2674665
Disease: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding)
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding) 		0.700 0
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.100 0.864 22 1996 2018
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 1.000 12 1996 2019
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.100 0.889 27 1998 2019
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.100 0.938 16 1998 2018
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.060 0.833 6 1999 2018
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		Nervous System Diseases; Cardiovascular Diseases 0.100 0.929 14 2000 2019
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.100 1.000 12 2000 2019
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.070 0.857 7 2000 2010
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		Cardiovascular Diseases 0.070 1.000 7 2000 2020
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0025945
Disease: Microangiopathy, Diabetic
Microangiopathy, Diabetic 		Endocrine System Diseases; Cardiovascular Diseases 0.020 1.000 2 2000 2018
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0025945
Disease: Microangiopathy, Diabetic
Microangiopathy, Diabetic 		Endocrine System Diseases; Cardiovascular Diseases 0.020 1.000 2 2000 2018
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		Cardiovascular Diseases 0.020 1.000 2 2000 2007
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.060 1.000 6 2001 2019
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.060 1.000 6 2001 2019
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.050 1.000 5 2001 2019
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.050 1.000 5 2001 2019
dbSNP: rs662
rs662 		0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42
CUI: C0007820
Disease: Cerebrovascular Disorders
Cerebrovascular Disorders 		Nervous System Diseases; Cardiovascular Diseases 0.020 0.500 2 2001 2018
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		Nervous System Diseases; Cardiovascular Diseases 0.020 0.500 2 2001 2004
dbSNP: rs854560
rs854560 		0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.100 0.909 11 2002 2017