SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs28914832
rs28914832 		0.925 0.120 17 30211356 missense variant T/C;G snv 7.4E-04
CUI: C4016373
Disease: OBSESSIVE-COMPULSIVE DISORDER, SUSCEPTIBILITY TO
OBSESSIVE-COMPULSIVE DISORDER, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs774676466
rs774676466 		17 30237267 upstream gene variant AGATGCTGGGGGGGCTGCAGGGGGGATGCTGGGGGTGCAGGGG/-;AGATGCTGGGGGGGCTGCAGGGGGGATGCTGGGGGTGCAGGGGAGATGCTGGGGGGGCTGCAGGGGGGATGCTGGGGGTGCAGGGG delins
CUI: C4016375
Disease: SEROTONIN TRANSPORTER ACTIVITY, INCREASED/DECREASED
SEROTONIN TRANSPORTER ACTIVITY, INCREASED/DECREASED 		0.700 0
dbSNP: rs6352
rs6352 		0.925 0.040 17 30203175 missense variant T/G snv 6.6E-03 4.4E-03
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		Mental Disorders 0.010 1.000 1 2006 2006
dbSNP: rs6352
rs6352 		0.925 0.040 17 30203175 missense variant T/G snv 6.6E-03 4.4E-03
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2006 2006
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0025193
Disease: Melancholia
Melancholia 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		Nervous System Diseases; Cardiovascular Diseases 0.010 1.000 1 2008 2008
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0154437
Disease: Atypical depressive disorder
Atypical depressive disorder 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0024517
Disease: Major depression, single episode
Major depression, single episode 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs4795541
rs4795541 		0.807 0.200 17 30237299 upstream gene variant A/G snv
CUI: C0751072
Disease: Frontotemporal Lobar Degeneration
Frontotemporal Lobar Degeneration 		Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0221480
Disease: Recurrent depression
Recurrent depression 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs2020936
rs2020936 		0.776 0.160 17 30223796 intron variant G/A;C snv
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		Digestive System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C1868717
Disease: Behavioural and psychiatric symptoms of dementia
Behavioural and psychiatric symptoms of dementia 		0.010 1.000 1 2009 2009
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0005874
Disease: Blushing
Blushing 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs25531
rs25531 		0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18
CUI: C0031572
Disease: Phobia, Social
Phobia, Social 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs6354
rs6354 		0.732 0.280 17 30222880 5 prime UTR variant G/C;T snv
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs6354
rs6354 		0.732 0.280 17 30222880 5 prime UTR variant G/C;T snv
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs6354
rs6354 		0.732 0.280 17 30222880 5 prime UTR variant G/C;T snv
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs6354
rs6354 		0.732 0.280 17 30222880 5 prime UTR variant G/C;T snv
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs6354
rs6354 		0.732 0.280 17 30222880 5 prime UTR variant G/C;T snv
CUI: C0221480
Disease: Recurrent depression
Recurrent depression 		Mental Disorders 0.010 1.000 1 2009 2009