TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs7901695
rs7901695 		0.851 0.160 10 112994329 intron variant T/C snv 0.34
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0020474
Disease: Hyperlipidemia, Familial Combined
Hyperlipidemia, Familial Combined 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C1842402
Disease: TROPICAL CALCIFIC PANCREATITIS
TROPICAL CALCIFIC PANCREATITIS 		Digestive System Diseases; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C2937224
Disease: Constitutional obesity
Constitutional obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C1281440
Disease: Familial obesity
Familial obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0271638
Disease: Type 2 diabetes mellitus in obese
Type 2 diabetes mellitus in obese 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs10885406
rs10885406 		0.925 0.120 10 113017965 intron variant A/G snv 0.55
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.020 1.000 2 2008 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.020 1.000 2 2008 2009
dbSNP: rs7904519
rs7904519 		0.763 0.240 10 113014168 intron variant A/G snv 0.55
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.700 1.000 2 2007 2009
dbSNP: rs10749127
rs10749127 		1.000 0.040 10 113089594 intron variant C/T snv 0.28
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.010 1.000 1 2009 2009
dbSNP: rs10885406
rs10885406 		0.925 0.120 10 113017965 intron variant A/G snv 0.55
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2009 2009
dbSNP: rs11196229
rs11196229 		0.925 0.160 10 113106413 intron variant G/A snv 0.19
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs11196229
rs11196229 		0.925 0.160 10 113106413 intron variant G/A snv 0.19
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs11196236
rs11196236 		0.925 0.160 10 113127963 intron variant T/C snv 0.16
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0342546
Disease: Premature adrenarche
Premature adrenarche 		0.010 1.000 1 2009 2009
dbSNP: rs3814570
rs3814570 		0.925 0.040 10 112948751 upstream gene variant C/T snv 0.23
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		Digestive System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs3814570
rs3814570 		0.925 0.040 10 112948751 upstream gene variant C/T snv 0.23
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		Digestive System Diseases 0.010 1.000 1 2009 2009
dbSNP: rs7901695
rs7901695 		0.851 0.160 10 112994329 intron variant T/C snv 0.34
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2009 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases 0.010 1.000 1 2009 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0342546
Disease: Premature adrenarche
Premature adrenarche 		0.010 1.000 1 2009 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2009 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C1272321
Disease: Autoantibody measurement
Autoantibody measurement 		0.700 1.000 1 2009 2009
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C4524040
Disease: Atherogenic dyslipidaemia
Atherogenic dyslipidaemia 		0.010 1.000 1 2009 2009
dbSNP: rs7924080
rs7924080 		0.925 0.120 10 113027253 intron variant T/C snv 0.55
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2009 2009