TLR3, toll like receptor 3, 7098

N. diseases: 393; N. variants: 24
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1554064929
rs1554064929 		1.000 4 186083922 stop gained G/T snv
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs199768900
rs199768900 		1.000 4 186084758 missense variant G/A snv 6.5E-04 5.9E-04
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs768091235
rs768091235 		1.000 4 186082765 missense variant T/C snv 2.4E-05 1.4E-05
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs121434431
rs121434431 		0.851 0.080 4 186083346 missense variant C/T snv 4.1E-04 5.2E-04
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 1.000 1 2007 2007
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0038522
Disease: Subacute Sclerosing Panencephalitis
Subacute Sclerosing Panencephalitis 		Infections; Nervous System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2011 2011
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C1504336
Disease: Polypoidal choroidal vasculopathy
Polypoidal choroidal vasculopathy 		0.010 < 0.001 1 2011 2011
dbSNP: rs11721827
rs11721827 		0.851 0.200 4 186069983 intron variant A/C snv 0.12
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs11721827
rs11721827 		0.851 0.200 4 186069983 intron variant A/C snv 0.12
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs11721827
rs11721827 		0.851 0.200 4 186069983 intron variant A/C snv 0.12
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		Immune System Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0019345
Disease: Herpes Labialis
Herpes Labialis 		Infections; Skin and Connective Tissue Diseases; Stomatognathic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0006271
Disease: Bronchiolitis
Bronchiolitis 		Infections; Respiratory Tract Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		Infections 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0006846
Disease: Cutaneous Candidiasis
Cutaneous Candidiasis 		Infections; Skin and Connective Tissue Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0857069
Disease: Chronic candidiasis
Chronic candidiasis 		Infections 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		Infections 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0043144
Disease: Wheezing
Wheezing 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0242510
Disease: Drug usage
Drug usage 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2012 2012
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C1274321
Disease: Recurrent herpes simplex labialis
Recurrent herpes simplex labialis 		Infections; Skin and Connective Tissue Diseases; Stomatognathic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3775292
rs3775292 		0.851 0.080 4 186081871 non coding transcript exon variant C/G snv 0.82
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs3775292
rs3775292 		0.851 0.080 4 186081871 non coding transcript exon variant C/G snv 0.82
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs3775292
rs3775292 		0.851 0.080 4 186081871 non coding transcript exon variant C/G snv 0.82
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs5743313
rs5743313 		0.851 0.200 4 186079213 intron variant C/T snv 0.19
CUI: C0155870
Disease: Pneumonia and influenza
Pneumonia and influenza 		Infections; Respiratory Tract Diseases 0.010 1.000 1 2012 2012