TLR3, toll like receptor 3, 7098

N. diseases: 393; N. variants: 24
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs121434431
rs121434431 		0.851 0.080 4 186083346 missense variant C/T snv 4.1E-04 5.2E-04
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 1.000 1 2007 2007
dbSNP: rs5743316
rs5743316 		4 186082537 missense variant A/T snv 4.0E-05 3.5E-05
CUI: C0428474
Disease: Serum LDL cholesterol measurement
Serum LDL cholesterol measurement 		0.700 1.000 1 2012 2012
dbSNP: rs5743316
rs5743316 		4 186082537 missense variant A/T snv 4.0E-05 3.5E-05
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.700 1.000 1 2012 2012
dbSNP: rs5743316
rs5743316 		4 186082537 missense variant A/T snv 4.0E-05 3.5E-05
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.700 1.000 1 2012 2012
dbSNP: rs1554064929
rs1554064929 		1.000 4 186083922 stop gained G/T snv
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs199768900
rs199768900 		1.000 4 186084758 missense variant G/A snv 6.5E-04 5.9E-04
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs768091235
rs768091235 		1.000 4 186082765 missense variant T/C snv 2.4E-05 1.4E-05
CUI: C2751803
Disease: HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2 		0.700 0
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		Digestive System Diseases; Infections 0.070 1.000 7 2009 2016
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		Eye Diseases 0.060 0.667 6 2008 2018
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C1536085
Disease: Geographic Atrophy
Geographic Atrophy 		Eye Diseases 0.030 1.000 3 2008 2016
dbSNP: rs13126816
rs13126816 		0.925 0.200 4 186073024 intron variant G/A snv 0.21
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.020 1.000 2 2014 2016
dbSNP: rs13126816
rs13126816 		0.925 0.200 4 186073024 intron variant G/A snv 0.21
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		Digestive System Diseases; Infections 0.020 1.000 2 2013 2015
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2011 2016
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		Digestive System Diseases; Infections 0.020 1.000 2 2016 2019
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2011 2016
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2015 2019
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2011 2016
dbSNP: rs3775290
rs3775290 		0.742 0.280 4 186083063 missense variant C/A;T snv 0.30
CUI: C0151517
Disease: Complete atrioventricular block
Complete atrioventricular block 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.020 1.000 2 2015 2016
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.020 1.000 2 2014 2016
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic 		Digestive System Diseases; Infections 0.020 1.000 2 2013 2018
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0014061
Disease: Tick-Borne Encephalitis
Tick-Borne Encephalitis 		Infections; Nervous System Diseases 0.020 1.000 2 2013 2017
dbSNP: rs3775291
rs3775291 		0.602 0.640 4 186082920 missense variant C/G;T snv 1.2E-04; 0.28
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		Digestive System Diseases; Infections 0.020 1.000 2 2013 2018
dbSNP: rs5743305
rs5743305 		0.807 0.200 4 186068179 upstream gene variant T/A snv 0.35
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		Digestive System Diseases; Infections 0.020 1.000 2 2009 2016
dbSNP: rs11721827
rs11721827 		0.851 0.200 4 186069983 intron variant A/C snv 0.12
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs11721827
rs11721827 		0.851 0.200 4 186069983 intron variant A/C snv 0.12
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012