|
rs1333049
|
CDKN2B-AS1
|
Coronary Artery Disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease.
|
29472232 |
2018 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary Artery Disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary heart disease
|
|
0.900 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary heart disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
|
rs10757274
|
CDKN2B-AS1
|
Coronary heart disease
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
|
22751097 |
2012 |
|
rs4977756
|
CDKN2B-AS1
|
Glioma
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association study of glioma and meta-analysis.
|
22886559 |
2012 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary heart disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
|
21606135 |
2011 |
|
rs4977756
|
CDKN2B-AS1
|
Glioma
|
G |
0.900 |
GeneticVariation |
GWASCAT |
We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).
|
19578367 |
2009 |
|
rs10757278
|
CDKN2B-AS1
|
Myocardial Infarction
|
G |
0.900 |
GeneticVariation |
GWASCAT |
A common variant on chromosome 9p21 affects the risk of myocardial infarction.
|
17478679 |
2007 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary heart disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
|
rs1333049
|
CDKN2B-AS1
|
Coronary heart disease
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Of thousands of chromosomal loci studied, the same locus had the strongest association with coronary artery disease in both the WTCCC and the German studies: chromosome 9p21.3 (SNP, rs1333049) (P=1.80x10(-14) and P=3.40x10(-6), respectively).
|
17634449 |
2007 |
|
rs4977574
|
CDKN2B-AS1
|
Coronary Artery Disease
|
A |
0.890 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs4977574
|
CDKN2B-AS1
|
Coronary Artery Disease
|
G |
0.890 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia.
|
29263402 |
2017 |
|
rs4977574
|
CDKN2B-AS1
|
Myocardial Infarction
|
G |
0.880 |
GeneticVariation |
GWASCAT |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
rs4977574
|
CDKN2B-AS1
|
Coronary heart disease
|
G |
0.840 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
|
rs4977574
|
CDKN2B-AS1
|
Coronary heart disease
|
G |
0.840 |
GeneticVariation |
GWASCAT |
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.
|
21239051 |
2011 |
|
rs4977574
|
CDKN2B-AS1
|
Coronary heart disease
|
G |
0.840 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
|
21378988 |
2011 |
|
rs1333040
|
CDKN2B-AS1
|
Intracranial Aneurysm
|
T |
0.840 |
GeneticVariation |
GWASCAT |
Genome-wide association study of intracranial aneurysm identifies three new risk loci.
|
20364137 |
2010 |
|
rs1333040
|
CDKN2B-AS1
|
Intracranial Aneurysm
|
T |
0.840 |
GeneticVariation |
GWASCAT |
Susceptibility loci for intracranial aneurysm in European and Japanese populations.
|
18997786 |
2008 |
|
rs2891168
|
CDKN2B-AS1
|
Coronary Artery Disease
|
A |
0.820 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs2891168
|
CDKN2B-AS1
|
Coronary Artery Disease
|
G |
0.820 |
GeneticVariation |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
rs2157719
|
CDKN2B-AS1
|
Glioma
|
C |
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple susceptibility loci for glioma.
|
26424050 |
2015 |
|
rs2891168
|
CDKN2B-AS1
|
Coronary Artery Disease
|
G |
0.820 |
GeneticVariation |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
rs1333042
|
CDKN2B-AS1
|
Coronary heart disease
|
|
0.820 |
GeneticVariation |
GWASCAT |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
rs10757272
|
CDKN2B-AS1
|
Intracranial Aneurysm
|
T |
0.820 |
GeneticVariation |
GWASCAT |
Additionally, we successfully replicated and validated rs10757272 on CDKN2BAS at chromosome 9p21.3 (combined P-value = 1.55 × 10(-7); odds ratio = 1.21) to be significantly associated with IA as previously reported.
|
22286173 |
2012 |