RPS10-NUDT3, RPS10-NUDT3 readthrough, 100529239

N. diseases: 8; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs28847046
rs28847046
Entrez Id: 100529239
Gene Symbol: RPS10-NUDT3
RPS10-NUDT3
CUI: C0017654
Disease:
Glomerular Filtration Rate 		C 0.700 GeneticVariation GWASCAT Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis. 31015462 2019
dbSNP: rs573582724
rs573582724
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs6935129
rs6935129
Entrez Id: 100529239
Gene Symbol: RPS10-NUDT3
RPS10-NUDT3
CUI: C0017654
Disease:
Glomerular Filtration Rate 		A 0.700 GeneticVariation GWASCAT Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. 30604766 2019
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs6935129
rs6935129
Entrez Id: 100529239
Gene Symbol: RPS10-NUDT3
RPS10-NUDT3
CUI: C0201976
Disease:
Creatinine measurement, serum (procedure) 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0005893
Disease:
Body mass index procedure 		0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0578022
Disease:
Finding of body mass index 		0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0005893
Disease:
Body mass index procedure 		G 0.700 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C1305855
Disease:
Body mass index 		G 0.700 GeneticVariation GWASCAT Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0578022
Disease:
Finding of body mass index 		G 0.700 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs267607021
rs267607021
Entrez Id: 6204;100529239
Gene Symbol: RPS10;RPS10-NUDT3
RPS10;RPS10-NUDT3
CUI: C2750081
Disease:
Diamond-Blackfan Anemia 9 		T 0.700 CausalMutation CLINVAR
dbSNP: rs267607022
rs267607022
Entrez Id: 6204;100529239
Gene Symbol: RPS10;RPS10-NUDT3
RPS10;RPS10-NUDT3
CUI: C2750081
Disease:
Diamond-Blackfan Anemia 9 		A 0.700 CausalMutation CLINVAR
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Five SNPs exhibited associations with pediatric-onset T2D in the combined case-parent trio and case-control analysis: LINGO/rs10968576 (odds ratio [OR] 1.82, P = 0.003), POC5/rs2112347 (OR 1.96, P = 2.4E-5), RPS10-NUDT3/rs206936 (OR 1.40, P = 0.023), GLIS3/rs7034200 (OR 2.34, P = 1.2E-6), and VEGFA/rs6905288 (OR 1.58, P = 0.015). 30652413 2019
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0424295
Disease:
Hyperactive behavior 		0.010 GeneticVariation BEFREE In the German sample rs206936 (NUDT3) and rs10938397 in the glucosamine-6-phosphate deaminase 2 gene (GNPDA2) were associated with inattention, whereas markers in the mitogen-activated protein kinase 5 gene (MAP2K5) and in the cell adhesion molecule 2 gene (CADM2) were associated with hyperactivity. 23533005 2013
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0424101
Disease:
Inattention 		0.010 GeneticVariation BEFREE In the German sample rs206936 (NUDT3) and rs10938397 in the glucosamine-6-phosphate deaminase 2 gene (GNPDA2) were associated with inattention, whereas markers in the mitogen-activated protein kinase 5 gene (MAP2K5) and in the cell adhesion molecule 2 gene (CADM2) were associated with hyperactivity. 23533005 2013
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C1263846
Disease:
Attention deficit hyperactivity disorder 		0.010 GeneticVariation BEFREE In the German sample rs206936 in the NUDT3 gene (nudix; nucleoside diphosphate linked moiety X-type motif 3) was associated with ADHD risk (OR: 1.39; P = 3.4 × 10(-4) ; Pcorr  = 0.01). 23533005 2013
dbSNP: rs206936
rs206936
Entrez Id: 11165;100529239
Gene Symbol: NUDT3;RPS10-NUDT3
NUDT3;RPS10-NUDT3
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE Eight loci, rs10968576 (BDNF), rs3817334 (MTCH2), rs1558902 (FTO), rs571312 (MC4R), rs543874 (SEC16B), rs987237 (TFAP2B), rs2867125 (TMEM18) and rs7138803 (FAIM2), were previously known obesity susceptibility loci, and the remaining four loci, rs1514175 (TNNI3K), rs206936 (NUDT3), rs4771122 (MTIF3) and rs2241423 (MAP2K5), were newly identified as BMI loci by the GIANT study. 22041983 2012