rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
In conclusion, some variants associated with CRC risk (rs10505477, rs6983267, rs10795668 and rs11255841) are also involved in the susceptibility to CRA and specific subtypes.
|
30194776 |
2019 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
G |
0.760 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the 8q24.21-rs6983267 polymorphism is associated with CRC/CRA susceptibility, but these associations vary in different ethnic populations.
|
24375194 |
2014 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
Three polymorphic sites at chromosome 8q24 (rs7837328, rs10808555, rs6983267) have been associated with risk for colorectal adenomas.
|
23776012 |
2014 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
There was a statistically significant direct association of rs6983267 with colorectal adenoma that was consistent with those in previous reports.
|
24115145 |
2014 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
We found no significant differences between the association of rs6983267 and colorectal cancer and colorectal adenomas.
|
21455501 |
2011 |
rs6983267
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
|
0.760 |
GeneticVariation |
BEFREE |
The combination of rs6983267 on 8q24.21 and rs9929218 on 16q22.2 was associated with a history of colorectal adenoma (carriers of GG and AA, respectively; OR, 2.28; 95% CI, 1.32-3.93; P = 5.0 x 10(-4)).
|
20638935 |
2010 |
rs7013278
|
POU5F1B;CASC8;PCAT1;CCAT2
|
Adenoma of large intestine
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
rs10505477
|
POU5F1B;CASC8;PCAT1
|
Adenoma of large intestine
|
|
0.020 |
GeneticVariation |
BEFREE |
Two SNPs (rs10505477, rs6983267) in the CASC8 gene were associated with a reduced risk of CRA in controls (log-additive models, OR: 0.67, 95%CI:0.54-0.83, and OR:0.66, 95%CI:0.54-0.84, respectively).
|
30194776 |
2019 |
rs10505477
|
POU5F1B;CASC8;PCAT1
|
Adenoma of large intestine
|
|
0.020 |
GeneticVariation |
BEFREE |
Two of these SNPs, rs10505477 and rs719725, showed evidence of an association in both CRC and CRA in our study population.
|
27769063 |
2016 |
rs10808555
|
POU5F1B;CASC8;PCAT1
|
Adenoma of large intestine
|
|
0.010 |
GeneticVariation |
BEFREE |
Three polymorphic sites at chromosome 8q24 (rs7837328, rs10808555, rs6983267) have been associated with risk for colorectal adenomas.
|
23776012 |
2014 |