AKAP9, A-kinase anchoring protein 9, 10142

N. diseases: 60; N. variants: 18
Disease: Malignant neoplasm of breast ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs756245027
rs756245027
Entrez Id: 10142
Gene Symbol: AKAP9
AKAP9
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs6964587
rs6964587
Entrez Id: 10142
Gene Symbol: AKAP9
AKAP9
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.020 GeneticVariation BEFREE For white European women, the minor T allele of 7q21-rs6964587 was associated with breast cancer risk under a recessive model (OR 1.07, 95% CI 1.00 to 1.13, p = 0.04). 21931171 2011
dbSNP: rs6964587
rs6964587
Entrez Id: 10142
Gene Symbol: AKAP9
AKAP9
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.020 GeneticVariation BEFREE The collaborative analysis confirmed the association of M463I with increased breast cancer risk. 18334708 2008
dbSNP: rs6960867
rs6960867
Entrez Id: 10142
Gene Symbol: AKAP9
AKAP9
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE To evaluate the impact of AKAP variants on breast cancer risk, we genotyped six nonsynonymous single-nucleotide polymorphisms that were predicted to be deleterious and found two (M463I, 1389G>T and N2792S, 8375A>G) to be associated with an allele dose-dependent increase in risk of familial breast cancer in a German population. 18334708 2008