CDK2, cyclin dependent kinase 2, 1017

N. diseases: 270; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2069408
rs2069408
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C0004096
Disease:
Asthma 		C 0.800 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548 2011
dbSNP: rs2069408
rs2069408
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C0004096
Disease:
Asthma 		C 0.800 GeneticVariation GWASDB Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548 2011
dbSNP: rs3213122
rs3213122
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs2069408
rs2069408
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.700 GeneticVariation GWASDB Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. 22885925 2012
dbSNP: rs1045435
rs1045435
Entrez Id: 1017;5869;6490
Gene Symbol: CDK2;RAB5B;PMEL
CDK2;RAB5B;PMEL
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.010 GeneticVariation BEFREE And <i>RAB5B</i> gene rs11550558, rs1045435, and rs11171718 SNPs were significantly associated with PCOS risk only in subjects with BMI ≥ 23.8 kg/m<sup>2</sup> We also found that the <i>RAB5B</i> gene rs1045435 SNP was associated with plasma miR-24 levels. 31036605 2019
dbSNP: rs1399364791
rs1399364791
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C0030297
Disease:
Pancreatic Neoplasm 		0.010 GeneticVariation BEFREE Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from Kras(G12D) mice. 25050737 2014
dbSNP: rs1399364791
rs1399364791
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C1335302
Disease:
Pancreatic Ductal Adenocarcinoma 		0.010 GeneticVariation BEFREE The chemopreventive efficacy of the statin atorvastatin (Lipitor(®)) and the role of the phosphatidyl-inositol 3-kinase (PI3/AKT) signaling pathway were evaluated for the progression of pancreatic intraepithelial neoplasms (PanINs) to pancreatic ductal adenocarcinoma (PDAC) in conditional p48(Cre/+) -LSL-Kras(G12D/+) transgenic mice. 22287227 2012
dbSNP: rs1399364791
rs1399364791
Entrez Id: 1017;6490
Gene Symbol: CDK2;PMEL
CDK2;PMEL
CUI: C1832661
Disease:
ANOPHTHALMIA AND PULMONARY HYPOPLASIA 		0.010 GeneticVariation BEFREE The chemopreventive efficacy of the statin atorvastatin (Lipitor(®)) and the role of the phosphatidyl-inositol 3-kinase (PI3/AKT) signaling pathway were evaluated for the progression of pancreatic intraepithelial neoplasms (PanINs) to pancreatic ductal adenocarcinoma (PDAC) in conditional p48(Cre/+) -LSL-Kras(G12D/+) transgenic mice. 22287227 2012