rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
BEFREE
(2) Four additional AD risk SNPs were nominally associated with obesity (rs17125944 at FERMT2, pBMI = 4.03 × 10(-05), pBMI corr = 2.50 × 10(-03) ; rs3851179 at PICALM; pBMI = 0.002, rs2075650 at TOMM40/APOE, pBMI = 0.024, rs3865444 at CD33, pBMI = 0.024).
24788522
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
BEFREE
Both methods' results showed two identical significant SNPs associated with the A β-42 levels in CSF (rs2075650 at intron region TOMM40 with p-value ≥ 1 × 10-16 and rs439401 in the intergenic region of LOC100129500 and APOC1 with p-value ≥ 1 × 10-9) and highlighted APOC1 and TOMM40, which are well-known genes previously associated with AD .
26576771
2016
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
BEFREE
Collectively, our analysis shows TOMM40 rs2075650 polymorphism is associated with AD susceptibility in Asian, Caucasian, and mixed populations.
27328316
2016
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
21460841
2011
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
G
0.900
GeneticVariation
GWASDB
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
20885792
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
G
0.900
GeneticVariation
GWASCAT
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
20885792
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.
26993346
2016
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
19136949
2009
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
G
0.900
GeneticVariation
GWASDB
Genome-wide analysis of genetic loci associated with Alzheimer disease.
20460622
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
G
0.900
GeneticVariation
GWASCAT
Genome-wide analysis of genetic loci associated with Alzheimer disease.
20460622
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
30636644
2019
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
22005931
2012
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
21379329
2011
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
19734903
2009
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
19734903
2009
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
19734902
2009
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
19734902
2009
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
22005930
2012
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide association study of Alzheimer's disease.
22832961
2012
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
21123754
2011
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
20061627
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
20061627
2010
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.
29107063
2018