PDLIM5, PDZ and LIM domain 5, 10611

N. diseases: 148; N. variants: 19
Disease: Hypertensive disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11097432
rs11097432
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Of the 25 SNPs, 5 SNPs showed associations with both AD in the SAGE sample and T2D in the Marshfield sample (top SNP rs11097432 with p = 0.00107 for T2D and p = 0.0483 for AD) while 6 SNPs showed associations with both AD in the SAGE sample and hypertension in the Marshfield sample (top SNP rs12500426 with p = 0.0119 for hypertension and p = 1.51 × 10<sup>-3</sup> for AD). 27693979 2017
dbSNP: rs12500426
rs12500426
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Of the 25 SNPs, 5 SNPs showed associations with both AD in the SAGE sample and T2D in the Marshfield sample (top SNP rs11097432 with p = 0.00107 for T2D and p = 0.0483 for AD) while 6 SNPs showed associations with both AD in the SAGE sample and hypertension in the Marshfield sample (top SNP rs12500426 with p = 0.0119 for hypertension and p = 1.51 × 10<sup>-3</sup> for AD). 27693979 2017
dbSNP: rs6532496
rs6532496
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE SNP (rs6532496) showed significant interaction with alcohol consumption for hypertension. 27693979 2017