STAG3, stromal antigen 3, 10734

N. diseases: 27; N. variants: 14
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17250196
rs17250196
Entrez Id: 10734;79037;352954
Gene Symbol: STAG3;PVRIG;CASTOR3
STAG3;PVRIG;CASTOR3
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4727449
rs4727449
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C0002395
Disease:
Alzheimer's Disease 		T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. 30617256 2019
dbSNP: rs7799441
rs7799441
Entrez Id: 10734;221914
Gene Symbol: STAG3;GPC2
STAG3;GPC2
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs79246196
rs79246196
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs79246196
rs79246196
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs79246196
rs79246196
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C1269683
Disease:
Major Depressive Disorder 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs79246196
rs79246196
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C0236664
Disease:
Alcohol-Related Disorders 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs17250196
rs17250196
Entrez Id: 10734;79037;352954
Gene Symbol: STAG3;PVRIG;CASTOR3
STAG3;PVRIG;CASTOR3
CUI: C0441683
Disease:
Hormone measurement 		0.700 GeneticVariation GWASDB Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. 21533175 2011
dbSNP: rs1333017606
rs1333017606
Entrez Id: 10734;221914
Gene Symbol: STAG3;GPC2
STAG3;GPC2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs376787666
rs376787666
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C3810367
Disease:
PREMATURE OVARIAN FAILURE 8 		A 0.700 CausalMutation CLINVAR
dbSNP: rs587777267
rs587777267
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C3810367
Disease:
PREMATURE OVARIAN FAILURE 8 		T 0.700 CausalMutation CLINVAR
dbSNP: rs764841861
rs764841861
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C0025322
Disease:
Premature Menopause 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs764841861
rs764841861
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C0021361
Disease:
Female infertility 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs764841861
rs764841861
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C4021818
Disease:
Abnormality of the ovary 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs869320765
rs869320765
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C3810367
Disease:
PREMATURE OVARIAN FAILURE 8 		CCT 0.700 CausalMutation CLINVAR
dbSNP: rs1052482
rs1052482
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C1847540
Disease:
Azoospermia, Nonobstructive 		0.010 GeneticVariation BEFREE We found that two SNVs (rs1727130 and rs1052482) located in the 3'-UTR region may be associated with the NOA phenotype. 31115363 2020
dbSNP: rs1727130
rs1727130
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C1847540
Disease:
Azoospermia, Nonobstructive 		0.010 GeneticVariation BEFREE We found that two SNVs (rs1727130 and rs1052482) located in the 3'-UTR region may be associated with the NOA phenotype. 31115363 2020
dbSNP: rs1161498711
rs1161498711
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C0021364
Disease:
Male infertility 		0.010 GeneticVariation BEFREE Two compound-heterozygous variants in STAG3 (c.[1262T>G];[1312C>T], p.[(Leu421Arg)];[(Arg438Ter)]) have been found to cause male infertility due to complete bilateral meiotic arrest in an otherwise healthy human male. 31682730 2019
dbSNP: rs751680143
rs751680143
Entrez Id: 10734;352954
Gene Symbol: STAG3;CASTOR3
STAG3;CASTOR3
CUI: C0021364
Disease:
Male infertility 		0.010 GeneticVariation BEFREE Two compound-heterozygous variants in STAG3 (c.[1262T>G];[1312C>T], p.[(Leu421Arg)];[(Arg438Ter)]) have been found to cause male infertility due to complete bilateral meiotic arrest in an otherwise healthy human male. 31682730 2019
dbSNP: rs11531577
rs11531577
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C0021364
Disease:
Male infertility 		0.010 GeneticVariation BEFREE The aim of this study was to explore the association between the SNP rs4045481 in RNF212 gene, rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene and male infertility with azoospermia in Chinese population. 29277047 2018
dbSNP: rs11531577
rs11531577
Entrez Id: 10734
Gene Symbol: STAG3
STAG3
CUI: C0004509
Disease:
Azoospermia 		0.010 GeneticVariation BEFREE No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed. 29277047 2018