PDE10A, phosphodiesterase 10A, 10846

N. diseases: 97; N. variants: 26
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs778899140
rs778899140
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310792
Disease:
DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET 		0.800 GeneticVariation UNIPROT Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy. 27058446 2016
dbSNP: rs753760
rs753760
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement 		C 0.800 GeneticVariation GWASDB A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
dbSNP: rs753760
rs753760
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement 		C 0.800 GeneticVariation GWASCAT A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
dbSNP: rs1039002
rs1039002
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005586
Disease:
Bipolar Disorder 		0.800 GeneticVariation GWASCAT Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸). 22205951 2011
dbSNP: rs1039002
rs1039002
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005586
Disease:
Bipolar Disorder 		0.800 GeneticVariation GWASDB Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸). 22205951 2011
dbSNP: rs7762160
rs7762160
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0149654
Disease:
Conduct Disorder 		C 0.800 GeneticVariation GWASCAT Genome-wide association study of conduct disorder symptomatology. 20585324 2011
dbSNP: rs7762160
rs7762160
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0149654
Disease:
Conduct Disorder 		0.800 GeneticVariation GWASDB Genome-wide association study of conduct disorder symptomatology. 20585324 2011
dbSNP: rs778899140
rs778899140
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310792
Disease:
DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET 		C 0.800 CausalMutation CLINVAR
dbSNP: rs875989839
rs875989839
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310792
Disease:
DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET 		0.800 GeneticVariation UNIPROT
dbSNP: rs875989839
rs875989839
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310792
Disease:
DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET 		G 0.800 CausalMutation CLINVAR
dbSNP: rs875989840
rs875989840
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310791
Disease:
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 		0.800 GeneticVariation UNIPROT
dbSNP: rs875989840
rs875989840
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310791
Disease:
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 		G 0.800 CausalMutation CLINVAR
dbSNP: rs875989841
rs875989841
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310791
Disease:
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 		0.800 GeneticVariation UNIPROT
dbSNP: rs875989841
rs875989841
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C4310791
Disease:
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 		G 0.800 CausalMutation CLINVAR
dbSNP: rs1079418
rs1079418
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0020676
Disease:
Hypothyroidism 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs221721
rs221721
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2934844
rs2934844
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005612
Disease:
Birth Weight 		T 0.700 GeneticVariation GWASCAT Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. 31043758 2019
dbSNP: rs2934849
rs2934849
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0007222
Disease:
Cardiovascular Diseases 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2983533
rs2983533
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3002433
rs3002433
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4305701
rs4305701
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs6914479
rs6914479
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs6932812
rs6932812
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7768382
rs7768382
Entrez Id: 10846;90632
Gene Symbol: PDE10A;LINC00473
PDE10A;LINC00473
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9457107
rs9457107
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
CUI: C0005612
Disease:
Birth Weight 		C 0.700 GeneticVariation GWASCAT Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. 31043758 2019