Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3769309
rs3769309
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
dbSNP: rs3769309
rs3769309
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
dbSNP: rs12996953
rs12996953
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs16861137
rs16861137
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0026654
Disease:
Moyamoya Disease 		A 0.700 GeneticVariation GWASCAT Novel Susceptibility Loci for Moyamoya Disease Revealed by a Genome-Wide Association Study. 29273593 2018
dbSNP: rs16861137
rs16861137
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C2931384
Disease:
Moyamoya disease 1 		A 0.700 GeneticVariation GWASCAT Novel Susceptibility Loci for Moyamoya Disease Revealed by a Genome-Wide Association Study. 29273593 2018
dbSNP: rs3769312
rs3769312
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs3769312
rs3769312
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs17746510
rs17746510
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0234985
Disease:
Mental deterioration 		0.010 GeneticVariation BEFREE Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. 27598965 2016
dbSNP: rs17746510
rs17746510
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. 27598965 2016
dbSNP: rs17746510
rs17746510
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0338656
Disease:
Impaired cognition 		0.010 GeneticVariation BEFREE Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. 27598965 2016
dbSNP: rs17746510
rs17746510
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C0085632
Disease:
Apathy 		0.010 GeneticVariation BEFREE Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. 27598965 2016
dbSNP: rs17746510
rs17746510
Entrez Id: 11069
Gene Symbol: RAPGEF4
RAPGEF4
CUI: C2939186
Disease:
Disturbance in mood 		0.010 GeneticVariation BEFREE Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. 27598965 2016