POU6F2, POU class 6 homeobox 2, 11281

N. diseases: 29; N. variants: 16
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1558162
rs1558162
Entrez Id: 11281;105375238
Gene Symbol: POU6F2;LOC105375238
POU6F2;LOC105375238
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.700 GeneticVariation GWASCAT Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. 30621171 2019
dbSNP: rs1558162
rs1558162
Entrez Id: 11281;105375238
Gene Symbol: POU6F2;LOC105375238
POU6F2;LOC105375238
CUI: C0344395
Disease:
Bilirubin measurement 		0.700 GeneticVariation GWASCAT Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. 30621171 2019
dbSNP: rs2140910
rs2140910
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2237403
rs2237403
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs3778934
rs3778934
Entrez Id: 11281;100861520
Gene Symbol: POU6F2;POU6F2-AS1
POU6F2;POU6F2-AS1
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3937443
rs3937443
Entrez Id: 11281;105375238
Gene Symbol: POU6F2;LOC105375238
POU6F2;LOC105375238
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.700 GeneticVariation GWASCAT Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. 30621171 2019
dbSNP: rs3937443
rs3937443
Entrez Id: 11281;105375238
Gene Symbol: POU6F2;LOC105375238
POU6F2;LOC105375238
CUI: C0344395
Disease:
Bilirubin measurement 		0.700 GeneticVariation GWASCAT Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. 30621171 2019
dbSNP: rs4072719
rs4072719
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0042834
Disease:
Vital capacity 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs58695218
rs58695218
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0037369
Disease:
Smoking 		A 0.700 GeneticVariation GWASCAT Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. 30643258 2019
dbSNP: rs952623
rs952623
Entrez Id: 11281;100689074
Gene Symbol: POU6F2;POU6F2-AS2
POU6F2;POU6F2-AS2
CUI: C0021704
Disease:
Intelligence 		C 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs10268735
rs10268735
Entrez Id: 11281;105375239
Gene Symbol: POU6F2;LOC105375239
POU6F2;LOC105375239
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs112503449
rs112503449
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs12674371
rs12674371
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0040420
Disease:
Tonometry 		0.700 GeneticVariation GWASCAT Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. 30054594 2018
dbSNP: rs28599716
rs28599716
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs62443626
rs62443626
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs6952464
rs6952464
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0040420
Disease:
Tonometry 		C 0.700 GeneticVariation GWASCAT Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. 29785010 2018
dbSNP: rs60464047
rs60464047
Entrez Id: 11281
Gene Symbol: POU6F2
POU6F2
CUI: C0026603
Disease:
Motion Sickness 		T 0.700 GeneticVariation GWASCAT Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis. 25628336 2015
dbSNP: rs121918261
rs121918261
Entrez Id: 11281;105375239
Gene Symbol: POU6F2;LOC105375239
POU6F2;LOC105375239
CUI: C1832099
Disease:
Wilms tumor and radial bilateral aplasia 		T 0.700 CausalMutation CLINVAR