DOCK1, dedicator of cytokinesis 1, 1793

N. diseases: 10; N. variants: 7
Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113847670
rs113847670
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0021655
Disease:
Insulin Resistance 		0.700 GeneticVariation GWASCAT Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women. 30327367 2019
dbSNP: rs113847670
rs113847670
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C1281901
Disease:
Fatty acid measurement 		0.700 GeneticVariation GWASCAT Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women. 30327367 2019
dbSNP: rs11017928
rs11017928
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0013264
Disease:
Muscular Dystrophy, Duchenne 		0.700 GeneticVariation GWASCAT Long-range genomic regulators of THBS1 and LTBP4 modify disease severity in duchenne muscular dystrophy. 30014611 2018
dbSNP: rs9794336
rs9794336
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs9794336
rs9794336
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs4751240
rs4751240
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0151544
Disease:
Gastrointestinal carcinoma 		0.700 GeneticVariation GWASCAT Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. 28044437 2017
dbSNP: rs4751240
rs4751240
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.700 GeneticVariation GWASCAT Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. 28044437 2017
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model. 27662902 2017
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model. 27662902 2017
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation. 26527617 2016
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation. 26527617 2016
dbSNP: rs115536975
rs115536975
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs115536975
rs115536975
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0037369
Disease:
Smoking 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs751008
rs751008
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Genetic studies of body mass index yield new insights for obesity biology. 25673413 2015
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Dock-family exchange factors in cell migration and disease. 25022758 2014
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR Dock-family exchange factors in cell migration and disease. 25022758 2014
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. 20829512 2010
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. 20829512 2010
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway. 18591431 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. 18820033 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway. 18591431 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. 18820033 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0432072
Disease:
Dysmorphic features 		TG 0.700 GeneticVariation CLINVAR Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. 18332221 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. 18332221 2008
dbSNP: rs767858333
rs767858333
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0000772
Disease:
Multiple congenital anomalies 		TG 0.700 GeneticVariation CLINVAR A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. 17670792 2007