DRD2, dopamine receptor D2, 1813

N. diseases: 437; N. variants: 42
Disease: Major Depressive Disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11214607
rs11214607
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085 2018
dbSNP: rs6277
rs6277
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.020 GeneticVariation BEFREE To conclude, this result suggests that Taq1A, C957T and -141C ins/del of DRD2 gene may not be associated with major depressive disorder, also may be the sample sizes too small to allow a meaningful test. 23696934 2013
dbSNP: rs6277
rs6277
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.020 GeneticVariation BEFREE Dopamine 2 receptor gene (DRD2) polymorphism C957T (rs6277) and cathechol-o-methyltransferase (COMT) polymorphism Val158Met (rs4680) interaction was studied in 118 patients suffering from major depressive disorder (MDD) treated with ECT and 383 healthy controls. 18929622 2008
dbSNP: rs6276
rs6276
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.010 GeneticVariation BEFREE Lack of influence of rs4680 (COMT) and rs6276 (DRD2) on diagnosis and clinical outcomes in patients with major depression. 24555772 2014