DRD3, dopamine receptor D3, 1814

N. diseases: 199; N. variants: 13
Disease: Alcoholic Intoxication, Chronic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6280
rs6280
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.020 GeneticVariation BEFREE DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans. 24776816 2014
dbSNP: rs6280
rs6280
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.020 GeneticVariation BEFREE We analyzed the -141C Ins/Del polymorphism in the promoter region of the DRD2 gene and the Ser9Gly (BalI) polymorphism in exon 1 of the DRD3 gene in 74 alcohol-dependent Caucasian men with or without genetic predisposition for alcoholism. 16759339 2006
dbSNP: rs2134655
rs2134655
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.010 GeneticVariation BEFREE The single-SNP analysis showed that the dominant minor allele of rs2134655 on DRD3 increases alcoholism susceptibility; the dominant minor allele of rs1439047 on NTRK2 delays the alcoholism onset age, but the additive minor allele of rs172677 on GRIN2B and the dominant minor allele of rs63319 on ALDH1A1 advance the alcoholism onset age; and the dominant minor allele of rs1079597 on DRD2 shortens the onset age range. 28512340 2017