AGTR1, angiotensin II receptor type 1, 185

N. diseases: 440; N. variants: 33
Disease: Aortic Aneurysm, Abdominal ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12695895
rs12695895
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0162871
Disease:
Aortic Aneurysm, Abdominal 		0.010 GeneticVariation BEFREE In this study of the Chinese population, homozygosity of TGFB1 rs1800469-T and AGTR1 rs12695895-T might be associated with increased risk of AAA. 26027897 2015
dbSNP: rs5186
rs5186
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0162871
Disease:
Aortic Aneurysm, Abdominal 		0.010 GeneticVariation BEFREE Genetic polymorphisms all previously reported as showing a significant correlation with AAA with functional effects on the expression or function were determined by analysis of the genomic DNA, including angiotensin 1 receptor (rs5186), interleukin-10 (IL-10; rs1800896), methyl-tetrahydrofolate reductase (rs1801133), low-density lipoprotein receptor-related protein 1 (LRP1; rs1466535), angiotensin-converting enzyme (rs1799752), and several matrix metalloproteinase 9 (MMP-9) single nucleotide polymorphisms. 24801553 2014