DisGeNET - a database of gene-disease associations

DYRK1A, dual specificity tyrosine phosphorylation regulated kinase 1A, 1859

N. diseases: 212; N. variants: 55

Disease: Global developmental delay ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs724159949

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044519

Entrez Id:	1859
Gene Symbol:	DYRK1A

DYRK1A

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044520

Entrez Id:	1859
Gene Symbol:	DYRK1A

DYRK1A

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044521

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044522

Entrez Id:	1859
Gene Symbol:	DYRK1A

DYRK1A

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044523

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044524

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

GeneticVariation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044525

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

GeneticVariation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs797044526

Entrez Id:	1859;105372797
Gene Symbol:	DYRK1A;LOC105372797

DYRK1A;LOC105372797

CUI:	C0557874
Disease:

Global developmental delay

0.700

GeneticVariation

CLINVAR

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.

25944381

2015

dbSNP:

rs1569355102

Entrez Id:	1859
Gene Symbol:	DYRK1A

DYRK1A

CUI:	C0557874
Disease:

Global developmental delay

0.700

CausalMutation

CLINVAR