MEGF6, multiple EGF like domains 6, 1953

N. diseases: 5; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12725009
rs12725009
Entrez Id: 1953
Gene Symbol: MEGF6
MEGF6
CUI: C0005689
Disease:
Bladder Exstrophy 		A 0.700 GeneticVariation GWASCAT Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy. 25763902 2015
dbSNP: rs947345
rs947345
Entrez Id: 1953
Gene Symbol: MEGF6
MEGF6
CUI: C2239176
Disease:
Liver carcinoma 		0.010 GeneticVariation BEFREE Seven polymorphisms of caspase 9 (rs2308941)C-->T and DOK2(rs2242241) T-->G, 6 of polymorphisms of EGFL3 (rs947345)A -->G, caspase 9 ( rs2308938) C-->G and PHGDH(rs1801955)T-->A, 5 of polymorphisms of E2F2(rs3218170) G-->A,4 of polymorphisms of MUTYH(rs1140507)T-->C and BNIP3L(rs1055806)G-->T, and 1 of polymorphism of TNFRSF1B (rs1061622)T-->G were detected by the chip in the tissues of 10 HCC. 16109524 2005