ERG, ETS transcription factor ERG, 2078

N. diseases: 298; N. variants: 31
Disease: Prostate carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs919467999
rs919467999
Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE We found two other EXO5 SNPs significantly associated with risk of PCa in cases-controls study from databases of genotype and phenotype (dbGaP), which are in linkage disequilibrium (D' = 1) with Exo5 L151P found in PCa family. 31616062 2020
dbSNP: rs746001963
rs746001963
Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE We identified a novel SPOP missense mutation (N296I) in a man with prostate cancer diagnosed at age 43. 24796539 2014
dbSNP: rs1004072779
rs1004072779
Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE Significant association of TMPRSS2-ERG fusion-positive PCa was found with rare variants in the genes for POLI [variant F532S: P = 0.0011; odds ratios (OR), 4.62; 95% confidence interval (95% CI), 1.84-11.56] and ESCO1 (variant N191S: P = 0.0034; OR, 4.27; 95% CI, 1.62-11.28). 19861517 2009