Disease: Malignant neoplasm of urinary bladder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3757441
rs3757441
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.010 GeneticVariation BEFREE Among the three polymorphic sites examined, the genotypes of EZH2 rs887569 (C to T), but not rs41277434 (A to C) or rs3757441 (T to C), were positively associated with bladder cancer risk (p for trend =0.0146). 27630289 2016
dbSNP: rs41277434
rs41277434
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.010 GeneticVariation BEFREE Among the three polymorphic sites examined, the genotypes of EZH2 rs887569 (C to T), but not rs41277434 (A to C) or rs3757441 (T to C), were positively associated with bladder cancer risk (p for trend =0.0146). 27630289 2016
dbSNP: rs887569
rs887569
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.010 GeneticVariation BEFREE Our findings provide evidence that the T allele of EZH2 rs887569 may be associated with the lower risk of bladder cancer development, especially among non-smokers. 27630289 2016