Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs142427338
rs142427338
Entrez Id: 219
Gene Symbol: ALDH1B1
ALDH1B1
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.010 GeneticVariation BEFREE The minor allele frequency of rs142427338 (Gln378Ter) was higher in alcohol dependent cases than in controls (allelic P = 0.19, OR = 2.98, [0.62-14.37]) but as this SNP is very rare the study was likely underpowered to detect an association with alcohol dependence risk. 28594837 2017
dbSNP: rs2073478
rs2073478
Entrez Id: 219
Gene Symbol: ALDH1B1
ALDH1B1
CUI: C0687132
Disease:
heavy drinking 		0.010 GeneticVariation BEFREE A protective effect on heavy drinking was found for the TT genotype of the ALDH1B1 arg107leu SNP (OR=0.59; 95% CI 0.37-0.92), present in 3% of pure Inuit and 37% of Danes. 25311581 2014
dbSNP: rs2073478
rs2073478
Entrez Id: 219
Gene Symbol: ALDH1B1
ALDH1B1
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE After assigning the most common allele combination as a reference, allele combination A-C-C-T-C-A, which simultaneously possessed the risk alleles of rs2073478 and rs671 polymorphisms, was associated with a 1.80-fold greater risk of CAD. 25047496 2014