STOX1, storkhead box 1, 219736

N. diseases: 39; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1163174
rs1163174
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10082399
rs10082399
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs1417941
rs1417941
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs1417941
rs1417941
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4320849
rs4320849
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs4746797
rs4746797
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs7083105
rs7083105
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs41278532
rs41278532
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C1836255
Disease:
Preeclampsia Eclampsia 4 		0.700 GeneticVariation UNIPROT Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. 15806103 2005
dbSNP: rs556362193
rs556362193
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C1836255
Disease:
Preeclampsia Eclampsia 4 		0.700 GeneticVariation UNIPROT Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. 15806103 2005
dbSNP: rs10509305
rs10509305
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C1836255
Disease:
Preeclampsia Eclampsia 4 		C 0.700 CausalMutation CLINVAR
dbSNP: rs1341667
rs1341667
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C1836255
Disease:
Preeclampsia Eclampsia 4 		C 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs1341667
rs1341667
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0013537
Disease:
Eclampsia 		0.020 GeneticVariation BEFREE The 10q22 chromosomal region with genomic linkage to pre-eclampsia in Dutch females shows a parent-of-origin effect with maternal transmission of the Y153H susceptibility allele of the STOX1 gene. 20716964 2011
dbSNP: rs1341667
rs1341667
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0013537
Disease:
Eclampsia 		0.020 GeneticVariation BEFREE By using complementary in vitro and ex vivo approaches, we show that the risk allele (Y153H) of the pre-eclampsia susceptibility gene STOX1 negatively regulates trophoblast invasion by upregulation of the cell-cell adhesion protein alpha-T-catenin (CTNNA3). 20400461 2010
dbSNP: rs10998461
rs10998461
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0281899
Disease:
Prolapsed lumbar disc 		0.010 GeneticVariation BEFREE In the haplotype analysis, the haplotype "GT" in block (rs10998461 and rs10998468) decreased LDH risk (OR = 0.7, 95% CI = 0.52-0.93, p = .016). 31724315 2020
dbSNP: rs10998468
rs10998468
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0281899
Disease:
Prolapsed lumbar disc 		0.010 GeneticVariation BEFREE In the haplotype analysis, the haplotype "GT" in block (rs10998461 and rs10998468) decreased LDH risk (OR = 0.7, 95% CI = 0.52-0.93, p = .016). 31724315 2020
dbSNP: rs4472827
rs4472827
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0281899
Disease:
Prolapsed lumbar disc 		0.010 GeneticVariation BEFREE Our results provide evidence for polymorphisms of rs7903209 and rs4472827 in STOX1 associated with LDH risk in Chinese Han population. 31724315 2020
dbSNP: rs7903209
rs7903209
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0281899
Disease:
Prolapsed lumbar disc 		0.010 GeneticVariation BEFREE Our results provide evidence for polymorphisms of rs7903209 and rs4472827 in STOX1 associated with LDH risk in Chinese Han population. 31724315 2020
dbSNP: rs1417939
rs1417939
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE Mean CRP levels were significantly elevated in men with one or two copies of the minor allele in rs3093075 and rs1417939, but these were unrelated to prostate cancer risk. 24844401 2014
dbSNP: rs1417939
rs1417939
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE Mean CRP levels were significantly elevated in men with one or two copies of the minor allele in rs3093075 and rs1417939, but these were unrelated to prostate cancer risk. 24844401 2014
dbSNP: rs1341667
rs1341667
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C1269955
Disease:
Tumor Cell Invasion 		0.010 GeneticVariation BEFREE By using complementary in vitro and ex vivo approaches, we show that the risk allele (Y153H) of the pre-eclampsia susceptibility gene STOX1 negatively regulates trophoblast invasion by upregulation of the cell-cell adhesion protein alpha-T-catenin (CTNNA3). 20400461 2010
dbSNP: rs1341667
rs1341667
Entrez Id: 219736
Gene Symbol: STOX1
STOX1
CUI: C0015934
Disease:
Fetal Growth Retardation 		0.010 GeneticVariation BEFREE In an isolated Dutch population, a distortion could not be demonstrated in the transmission of STOX1-Y153H variation from heterozygous mothers to offspring in 50 and 56 families with pregnancies complicated by pre-eclampsia or intrauterine growth restriction, respectively. 17617193 2007