FGFR2, fibroblast growth factor receptor 2, 2263

N. diseases: 731; N. variants: 141
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2981582
rs2981582
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE Single Nucleotide Polymorphisms (SNPs) of P53 Pro72Arg, MDM2 SNP309, P21 Ser31Arg, ER SNP594, HER2 Ile655Val, and FGFR2 rs2981582 have drawn attention as genetic factors associated with cancer risk. 31759353 2019
dbSNP: rs2981582
rs2981582
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE The logistic regression confirmed that rs2981582 FGFR2 polymorphism (OR = 2.09; 95 % CI 1.35, 3.20) and the interaction between rs1056663 and rs2708861 HUS1 polymorphisms increased the risk of cancer (OR = 1.87; 95 % CI 1.19, 2.92). 22926736 2012
dbSNP: rs374608214
rs374608214
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Single Nucleotide Polymorphisms (SNPs) of P53 Pro72Arg, MDM2 SNP309, P21 Ser31Arg, ER SNP594, HER2 Ile655Val, and FGFR2 rs2981582 have drawn attention as genetic factors associated with cancer risk. 31759353 2019
dbSNP: rs747718232
rs747718232
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Single Nucleotide Polymorphisms (SNPs) of P53 Pro72Arg, MDM2 SNP309, P21 Ser31Arg, ER SNP594, HER2 Ile655Val, and FGFR2 rs2981582 have drawn attention as genetic factors associated with cancer risk. 31759353 2019
dbSNP: rs779848635
rs779848635
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Single Nucleotide Polymorphisms (SNPs) of P53 Pro72Arg, MDM2 SNP309, P21 Ser31Arg, ER SNP594, HER2 Ile655Val, and FGFR2 rs2981582 have drawn attention as genetic factors associated with cancer risk. 31759353 2019
dbSNP: rs121913474
rs121913474
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE FGFR2 p.Cys382Arg is a known somatic driver mutation in human cancer, previously reported to result in activation of RAS signalling. 27095246 2017
dbSNP: rs1219648
rs1219648
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Previous studies have suggested associations between rs11200014, rs2981579, and rs1219648 polymorphisms and cancer risk. 29390357 2017