FGFR4, fibroblast growth factor receptor 4, 2264

N. diseases: 220; N. variants: 19
Disease: Tumor Progression ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs351855
rs351855
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
CUI: C0178874
Disease:
Tumor Progression 		0.030 GeneticVariation BEFREE Thus, our findings elucidate the molecular mechanism behind the genetic association of rs351855 with accelerated cancer progression and suggest that germline variants of cell-surface molecules that recruit STAT3 to the inner cell membrane are a significant risk for cancer prognosis and disease progression. 26675719 2015
dbSNP: rs351855
rs351855
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
CUI: C0178874
Disease:
Tumor Progression 		0.030 GeneticVariation BEFREE This LOH involved the FGFR4-WT allele as frequently as the cancer progression-associated FGFR4-G388R polymorphic allele. 21037081 2010
dbSNP: rs351855
rs351855
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
CUI: C0178874
Disease:
Tumor Progression 		0.030 GeneticVariation BEFREE Three other nonparametric linear rank-tests particularly suitable for investigating possible relations between G388R mutation and early cancer progression were also used. 14710228 2004