FGG, fibrinogen gamma chain, 2266

N. diseases: 70; N. variants: 18
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE Fibrinogen gamma gene rs2066865 and risk of cancer-related venous thromboembolism. 31582554 2019
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11). 31124268 2019
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		A 0.860 GeneticVariation GWASCAT Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. 31676865 2019
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE A nominal significant association with VTE was found for the FGG rs2066865 minor T-allele in the dominant model (OR 1.82; P = 0.034). 29995659 2018
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		A 0.860 GeneticVariation GWASCAT Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. 28373160 2017
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE Finally, our study demonstrated the important role of rs2289252, rs2036914, rs2066865, and rs13146272 polymorphisms in the development of VTE in the white race. 28353616 2017
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE In both race groups, the minor allele of FGG rs2066865 was associated with lower γ' fibrinogen concentrations, but this allele was not associated with VTE. 26916295 2016
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		A 0.860 GeneticVariation GWASCAT Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. 25772935 2015
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation BEFREE We investigated the VTE risk associated with SNPs in the GP6 (rs1613662), SERPINC1 (rs2227589), F11 (rs2036914 and rs2289252), FGG (rs2066865), and F12 (rs1801020) genes. 23150947 2013
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.860 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494 2011
dbSNP: rs2066864
rs2066864
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		A 0.800 GeneticVariation GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334 2019
dbSNP: rs2066864
rs2066864
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1861172
Disease:
Venous Thromboembolism 		0.800 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494 2011
dbSNP: rs121913087
rs121913087
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0553681
Disease:
Hypofibrinogenemia 		A 0.700 CausalMutation CLINVAR Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. 31064749 2019
dbSNP: rs121913088
rs121913088
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0553681
Disease:
Hypofibrinogenemia 		T 0.700 CausalMutation CLINVAR Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. 31064749 2019
dbSNP: rs148685782
rs148685782
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1458140
Disease:
Bleeding tendency 		C 0.700 GeneticVariation CLINVAR Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. 31064749 2019
dbSNP: rs148685782
rs148685782
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0523677
Disease:
Glycine measurement 		G 0.700 GeneticVariation GWASCAT Assessing the causal association of glycine with risk of cardio-metabolic diseases. 30837465 2019
dbSNP: rs587776837
rs587776837
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0553681
Disease:
Hypofibrinogenemia 		T 0.700 GeneticVariation CLINVAR Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. 31064749 2019
dbSNP: rs148685782
rs148685782
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0337428
Disease:
Fibrinogen assay 		C 0.700 GeneticVariation GWASCAT A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. 26561523 2016
dbSNP: rs75848804
rs75848804
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C2584774
Disease:
Congenital hypofibrinogenemia 		0.700 GeneticVariation UNIPROT Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency. 25427968 2015
dbSNP: rs2066854
rs2066854
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0042487
Disease:
Venous Thrombosis 		0.700 GeneticVariation GWASDB Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. 22675575 2012
dbSNP: rs2066861
rs2066861
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0042487
Disease:
Venous Thrombosis 		0.700 GeneticVariation GWASDB Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. 22675575 2012
dbSNP: rs2066864
rs2066864
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0042487
Disease:
Venous Thrombosis 		0.700 GeneticVariation GWASDB Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. 22675575 2012
dbSNP: rs2066865
rs2066865
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0042487
Disease:
Venous Thrombosis 		0.700 GeneticVariation GWASDB Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. 22675575 2012
dbSNP: rs2066861
rs2066861
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C0337428
Disease:
Fibrinogen assay 		0.700 GeneticVariation GWASDB The association of FGG rs2066861 with fibrinogen differed according to assay type used to measure fibrinogen. 20978265 2011
dbSNP: rs2066861
rs2066861
Entrez Id: 2266
Gene Symbol: FGG
FGG
CUI: C1561955
Disease:
Fibrinogen, CTCAE 		0.700 GeneticVariation GWASDB The association of FGG rs2066861 with fibrinogen differed according to assay type used to measure fibrinogen. 20978265 2011