KIFAP3, kinesin associated protein 3, 22920

N. diseases: 19; N. variants: 5
Disease: Amyotrophic Lateral Sclerosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1541160
rs1541160
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.830 GeneticVariation BEFREE In a previous large multicenter genome wide study, common genetic variation in the Kinesin-Associated Protein 3 (KIFAP3) gene (rs1541160) was reported to have a significant effect on survival in amyotrophic lateral sclerosis patients. 24838185 2014
dbSNP: rs1541160
rs1541160
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.830 GeneticVariation BEFREE The incidence of the UMN-ALS phenotype in the CC patients of this cohort supports the hypothesis that the SNP rs1541160 within the KIFAP3 gene is a potential modifier of the ALS phenotype. 21659726 2011
dbSNP: rs1541160
rs1541160
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.830 GeneticVariation BEFREE It was recently reported that rs1541160 on chromosome 1q24.2 has a marked effect on survival of amyotrophic lateral sclerosis (ALS) patients by influencing KIFAP3 expression. 20566859 2010
dbSNP: rs1541160
rs1541160
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		C 0.830 GeneticVariation GWASCAT Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. 19451621 2009
dbSNP: rs1541160
rs1541160
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		C 0.830 GeneticVariation GWASDB Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. 19451621 2009