CEP68, centrosomal protein 68, 23177

N. diseases: 13; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs111524356
rs111524356
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0871470
Disease:
Systolic Pressure 		CGTGGATGCAGCA 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019
dbSNP: rs2249105
rs2249105
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs111524356
rs111524356
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs2249105
rs2249105
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880 2018
dbSNP: rs2249105
rs2249105
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880 2018
dbSNP: rs2249105
rs2249105
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880 2018
dbSNP: rs2249105
rs2249105
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880 2018
dbSNP: rs2540948
rs2540948
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.700 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
dbSNP: rs2540949
rs2540949
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0004238
Disease:
Atrial Fibrillation 		A 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
dbSNP: rs2540949
rs2540949
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0004238
Disease:
Atrial Fibrillation 		A 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs6728523
rs6728523
Entrez Id: 23177;400958;107984063
Gene Symbol: CEP68;LINC02245;LOC107984063
CEP68;LINC02245;LOC107984063
CUI: C0392885
Disease:
High density lipoprotein measurement 		C 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs7572857
rs7572857
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.700 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382 2018
dbSNP: rs2540949
rs2540949
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0004238
Disease:
Atrial Fibrillation 		A 0.700 GeneticVariation GWASCAT Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. 28416818 2017
dbSNP: rs2540948
rs2540948
Entrez Id: 23177;107984063
Gene Symbol: CEP68;LOC107984063
CEP68;LOC107984063
CUI: C0202236
Disease:
Triglycerides measurement 		C 0.700 GeneticVariation GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
dbSNP: rs7572857
rs7572857
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0004059
Disease:
aspirin intolerance 		0.020 GeneticVariation BEFREE We found in the MNSAID-UA group a number of variants (17) associated (lowest p-value = 1.13 × 10(-6)), including the non-synonymous Gly74Ser variant (rs7572857) previously associated with aspirin intolerance susceptibility in asthmatics. 24618698 2014
dbSNP: rs7572857
rs7572857
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0004059
Disease:
aspirin intolerance 		0.020 GeneticVariation BEFREE Our findings imply that CEP68 could be a susceptible gene for aspirin intolerance in asthmatics, suggesting that the nonsynonymous Gly74Ser could affect the polarity of the protein structure. 21072201 2010
dbSNP: rs7572857
rs7572857
Entrez Id: 23177
Gene Symbol: CEP68
CEP68
CUI: C0004096
Disease:
Asthma 		0.010 GeneticVariation BEFREE We found in the MNSAID-UA group a number of variants (17) associated (lowest p-value = 1.13 × 10(-6)), including the non-synonymous Gly74Ser variant (rs7572857) previously associated with aspirin intolerance susceptibility in asthmatics. 24618698 2014