Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.840 GeneticVariation BEFREE rs2903692 conferred a protective effect on patients with T1D, MS and RA. 19221398 2010
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.840 GeneticVariation BEFREE Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692). 19337309 2009
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.840 GeneticVariation BEFREE Furthermore, a joint analysis, with the INS and CTLA4 SNPs, revealed that CTLA4 rs3087243, ERBB3 rs2292399, and CLEC16A rs2903692, but not INS rs689, were significant risk factors for the cooccurrence of AITD in Japanese T1D. 18940880 2009
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.840 GeneticVariation GWASCAT Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.840 GeneticVariation BEFREE Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.840 GeneticVariation GWASDB Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs12927355
rs12927355
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		C 0.800 GeneticVariation GWASCAT Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. 25751624 2015
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.800 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393 2011
dbSNP: rs12927355
rs12927355
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.800 GeneticVariation GWASDB A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. 21980299 2011
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.800 GeneticVariation GWASDB Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.800 GeneticVariation GWASCAT Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.800 GeneticVariation GWASDB Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.800 GeneticVariation GWASCAT Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		A 0.800 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300 2007
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		A 0.800 GeneticVariation GWASDB Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300 2007
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		A 0.800 GeneticVariation GWASCAT Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. 17554260 2007
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		A 0.800 GeneticVariation GWASDB Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. 17554260 2007
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.740 GeneticVariation BEFREE Our results demonstrated that IL2RA rs11594656 and CLEC16A rs725613 are protective factors of T1D, while NLRP1 rs12150220 and APOA5 -1131T/C are risky factors of T1D and T2D, respectively. 23922971 2013
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.740 GeneticVariation BEFREE In these Sardinian samples, allele A of rs725613 is positively associated not only with T1D (odds ratio=1.15, P one-tail=5.1 x 10(-3)) but also, and with a comparable effect size, with MS (odds ratio=1.21, P one-tail 6.7 x 10(-5)). 18946483 2009
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.740 GeneticVariation BEFREE The intron polymorphism rs725613 in the KIAA0350 gene is associated with susceptibility to T1D, and this association is not race specific. 19178520 2009
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.740 GeneticVariation BEFREE Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.740 GeneticVariation GWASDB Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs17673553
rs17673553
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.710 GeneticVariation GWASDB Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs17673553
rs17673553
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.710 GeneticVariation BEFREE Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D. 17632545 2007
dbSNP: rs12599402
rs12599402
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASDB A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. 17632545 2007