SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Acute Chest Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3758391
rs3758391
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0742343
Disease:
Acute Chest Syndrome 		0.010 GeneticVariation BEFREE The present results confirm that the SIRT1 gene plays a protective role against ACS and that the rs3758391 SNP affects the mRNA expression in healthy participants, providing new insight into the processes regulating the genetic control of the SIRT1 gene with respect to the pathogenesis of ACS. 25342474 2015