FOLR2, folate receptor beta, 2350

N. diseases: 105; N. variants: 4
Disease: Neural Tube Defects ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs651646
rs651646
Entrez Id: 2350
Gene Symbol: FOLR2
FOLR2
CUI: C0027794
Disease:
Neural Tube Defects 		0.010 GeneticVariation BEFREE In conclusion, SNP rs651646 within the FRbeta gene is polymorphic but is not associated with neural tube defects within the Irish population. 12809644 2003
dbSNP: rs1203798584
rs1203798584
Entrez Id: 2350
Gene Symbol: FOLR2
FOLR2
CUI: C0027794
Disease:
Neural Tube Defects 		0.010 GeneticVariation BEFREE Recently we discovered the first genetic risk factors for NTDs: the 677 C-->T and the 1298 A-->C mutations in the methylenetetrahydrofolate reductase gene explaining at the most 35-50% of the protective effect of folate. 10234517 1999