PRKD2, protein kinase D2, 25865

N. diseases: 40; N. variants: 12
Disease: Chronic Lymphocytic Leukemia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11083846
rs11083846
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.830 GeneticVariation BEFREE Common single nucleotide polymorphisms (SNPs) at 2q13 (rs17483466), 2q37.1 (rs13397985), 2q37.3 (rs757978), 6p25.3 (rs872071), 8q24.21 (rs2456449), 11q24.1 (rs735665), 15q21.3 (rs7169431), 15q23 (rs7176508), 16q24.1 (rs305061), and 19q13.32 (rs11083846) have been shown to confer a modest but significant increase in CLL risk. 20855867 2010
dbSNP: rs11083846
rs11083846
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.830 GeneticVariation BEFREE Combined data provided statistically significant support for an association between genotypes at rs13397985, rs872071, rs735665, rs7176508 and rs11083846 and CLL risk. 20553269 2010
dbSNP: rs11083846
rs11083846
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		A 0.830 GeneticVariation GWASCAT We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008
dbSNP: rs11083846
rs11083846
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		A 0.830 GeneticVariation GWASDB We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008
dbSNP: rs11083846
rs11083846
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.830 GeneticVariation BEFREE We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008