Disease: Coronary heart disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		0.830 GeneticVariation BEFREE We investigated the association between rs6922269 and known metabolic risk factors and survival in two independent cohorts of coronary heart disease patients. 24618918 2014
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		0.830 GeneticVariation BEFREE The Ch9p21 SNPs rs1333049 (OR 1.17; 95% confidence limits 1.11-1.24) and rs10757274 (OR 1.17; 1.09-1.26), MIA3 rs17465637 (OR 1.10; 1.04-1.15), Ch2q36 rs2943634 (OR 1.08; 1.03-1.14), APC rs383830 (OR 1.10; 1.02, 1.18), MTHFD1L rs6922269 (OR 1.10; 1.03, 1.16), CXCL12 rs501120 (OR 1.12; 1.04, 1.20), and SMAD3 rs17228212 (OR 1.11; 1.05, 1.17) were all associated with CHD risk, but not with the CHD biomarkers and risk factors measured. 21804106 2012
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		0.830 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		0.830 GeneticVariation BEFREE Nine loci were statistically associated with incident CHD events in white participants: 9p21 (rs10757278; P=4.7 × 10(-41)), 16q23.1 (rs2549513; P=0.0004), 6p24.1 (rs499818; P=0.0002), 2q36.3 (rs2943634; P=6.7 × 10(-6)), MTHFD1L (rs6922269, P=5.1 × 10(-10)), APOE (rs429358; P=2.7×10(-18)), ZNF627 (rs4804611; P=5.0 × 10(-8)), CXCL12 (rs501120; P=1.4 × 10(-6)) and LPL (rs268; P=2.7 × 10(-17)). 22042884 2011
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		A 0.830 GeneticVariation GWASDB Genomewide association analysis of coronary artery disease. 17634449 2007
dbSNP: rs6922269
rs6922269
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
CUI: C0010068
Disease:
Coronary heart disease 		A 0.830 GeneticVariation GWASCAT Genomewide association analysis of coronary artery disease. 17634449 2007