DisGeNET - a database of gene-disease associations

MTHFD1L, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like, 25902

N. diseases: 41; N. variants: 14

Disease: Coronary Artery Disease ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs6907487

Entrez Id:	25902
Gene Symbol:	MTHFD1L

MTHFD1L

CUI:	C1956346
Disease:

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs9371203

Entrez Id:	25902
Gene Symbol:	MTHFD1L

MTHFD1L

CUI:	C1956346
Disease:

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs6922269

Entrez Id:	25902
Gene Symbol:	MTHFD1L

MTHFD1L

CUI:	C1956346
Disease:

Coronary Artery Disease

0.020

GeneticVariation

BEFREE

Polymorphisms in MTHFD1L, including rs6922269</span>, have been implicated in risk for coronary artery disease (CAD).

24618918

2014

dbSNP:

rs6922269

Entrez Id:	25902
Gene Symbol:	MTHFD1L

MTHFD1L

CUI:	C1956346
Disease:

Coronary Artery Disease

0.020

GeneticVariation

BEFREE

Variant rs6922269 in neither cohort was significantly associated with CAD.

19135198

2009