DisGeNET - a database of gene-disease associations

LRIG1, leucine rich repeats and immunoglobulin like domains 1, 26018

N. diseases: 83; N. variants: 13

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11706832

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0017638
Disease:

Glioma

0.710

GeneticVariation

BEFREE

Thus, for the first time, changes in physiological Lrig1 expression have been linked to gliomagenesis, whereby the SNP rs11706832 may affect glioma risk by regulating LRIG1 expression.

29391393

2018

dbSNP:

rs11706832

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0017638
Disease:

Glioma

0.710

GeneticVariation

GWASCAT

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

28346443

2017

dbSNP:

rs2306272

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs3965156

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0005612
Disease:

Birth Weight

0.700

GeneticVariation

GWASCAT

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

31043758

2019

dbSNP:

rs6549120

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C1261502
Disease:

Finding of Mean Corpuscular Hemoglobin

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C2677123
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 3

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C2675481
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 10

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C1837315
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 1

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0346629
Disease:

Malignant neoplasm of large intestine

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C1319315
Disease:

Adenocarcinoma of large intestine

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0009402
Disease:

Colorectal Carcinoma

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C3554460
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 12

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs812481

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0007102
Disease:

Malignant tumor of colon

0.700

GeneticVariation

GWASCAT

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

29917119

2019

dbSNP:

rs147372871

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0022661
Disease:

Kidney Failure, Chronic

0.700

GeneticVariation

GWASCAT

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

29124443

2018

dbSNP:

rs202007714

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0201976
Disease:

Creatinine measurement, serum (procedure)

0.700

GeneticVariation

GWASCAT

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

29124443

2018

dbSNP:

rs202007714

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0017654
Disease:

Glomerular Filtration Rate

0.700

GeneticVariation

GWASCAT

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

29124443

2018

dbSNP:

rs202007714

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0202239
Disease:

Uric acid measurement (procedure)

0.700

GeneticVariation

GWASCAT

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

29124443

2018

dbSNP:

rs202007714

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0740394
Disease:

Hyperuricemia

0.700

GeneticVariation

GWASCAT

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

29124443

2018

dbSNP:

rs2306272

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Multi-ethnic genome-wide association study for atrial fibrillation.

29892015

2018

dbSNP:

rs34080181

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

30061737

2018

dbSNP:

rs11706832

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C0085136
Disease:

Central Nervous System Neoplasms

0.700

GeneticVariation

GWASCAT

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

28346443

2017

dbSNP:

rs17831815

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

27841878

2017

dbSNP:

rs2242285

Entrez Id:	26018;115286
Gene Symbol:	LRIG1;SLC25A26

LRIG1;SLC25A26

CUI:	C0429097
Disease:

QRS complex feature

0.700

GeneticVariation

GWASCAT

52 Genetic Loci Influencing Myocardial Mass.

27659466

2016

dbSNP:

rs6147862

Entrez Id:	26018
Gene Symbol:	LRIG1

LRIG1

CUI:	C1261502
Disease:

Finding of Mean Corpuscular Hemoglobin

0.700

GeneticVariation

GWASCAT

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

27863252

2016