DisGeNET - a database of gene-disease associations

GCKR, glucokinase regulator, 2646

N. diseases: 136; N. variants: 23

Disease: Triglycerides measurement ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association study of blood lipids in Indians confirms universality of established variants.

30911093

2019

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

30926973

2019

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

30670697

2019

dbSNP:

rs780092

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

30718733

2019

dbSNP:

rs780093

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs780094

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

30275531

2018

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs780092

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.

29404214

2018

dbSNP:

rs780092

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.

29615537

2018

dbSNP:

rs780093

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs780094

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.

29615537

2018

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017

dbSNP:

rs780094

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017

dbSNP:

rs814295

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.

27286809

2016

dbSNP:

rs780093

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

26780889

2016

dbSNP:

rs780094

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.

27790247

2016

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

The impact of low-frequency and rare variants on lipid levels.

25961943

2015

dbSNP:

rs780093

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3.

26160806

2015

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

23505323

2013

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs1260326

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

A genome wide association study identifies common variants associated with lipid levels in the Chinese population.

24386095

2013