DisGeNET - a database of gene-disease associations

KANSL1, KAT8 regulatory NSL complex subunit 1, 284058

N. diseases: 140; N. variants: 332

Disease: Parkinson Disease ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs17577094

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.800

GeneticVariation

GWASCAT

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.

24842889

2014

dbSNP:

rs17577094

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.800

GeneticVariation

GWASDB

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.

24842889

2014

dbSNP:

rs17574228

Entrez Id:	4137;284058
Gene Symbol:	MAPT;KANSL1

MAPT;KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs17574361

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs17574604

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs2668692

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs546433642

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs549599956

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs7225002

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

22438815

2012

dbSNP:

rs2668692

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs544161107

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs546433642

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs549599956

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs7225002

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

21738487

2011

dbSNP:

rs2668692

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs546433642

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs549599956

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs7225002

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.700

GeneticVariation

GWASDB

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

19915575

2009

dbSNP:

rs541455835

Entrez Id:	284058
Gene Symbol:	KANSL1

KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.010

GeneticVariation

BEFREE

This includes the rs541455835 variant at the MAPT locus encoding the Tau protein associated with Parkinson's disease.

29669022

2018

dbSNP:

rs7521

Entrez Id:	4137;284058
Gene Symbol:	MAPT;KANSL1

MAPT;KANSL1

CUI:	C0030567
Disease:

Parkinson Disease

0.010

GeneticVariation

BEFREE

This observation highlights the significance of rs7521 in modifying the age at onset of PD under a common haplotype background.

19450659

2009