DisGeNET - a database of gene-disease associations

HCG22, HLA complex group 22 (gene/pseudogene), 285834

N. diseases: 20; N. variants: 12

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.800

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262632

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.800

GeneticVariation

GWASCAT

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs9262631

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0018213
Disease:

Graves Disease

0.700

GeneticVariation

GWASCAT

Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.

26151496

2015

dbSNP:

rs9262631

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0272178
Disease:

Drug-induced neutropenia

0.700

GeneticVariation

GWASCAT

Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.

26151496

2015

dbSNP:

rs4713429

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0007193
Disease:

Cardiomyopathy, Dilated

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.

23853074

2014

dbSNP:

rs9262615

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0007193
Disease:

Cardiomyopathy, Dilated

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.

23853074

2014

dbSNP:

rs9262635

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0007193
Disease:

Cardiomyopathy, Dilated

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.

23853074

2014

dbSNP:

rs9262636

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0007193
Disease:

Cardiomyopathy, Dilated

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.

23853074

2014

dbSNP:

rs9262638

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0020676
Disease:

Hypothyroidism

0.700

GeneticVariation

GWASDB

Novel associations for hypothyroidism include known autoimmune risk loci.

22493691

2012

dbSNP:

rs9262639

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0020676
Disease:

Hypothyroidism

0.700

GeneticVariation

GWASDB

Novel associations for hypothyroidism include known autoimmune risk loci.

22493691

2012

dbSNP:

rs16898614

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836232
Disease:

ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs16898614

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836230
Disease:

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs16898614

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836233
Disease:

AIDS, PROGRESSION TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs16898614

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C1836231
Disease:

HIV-1, RESISTANCE TO

0.700

GeneticVariation

GWASDB

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

21051598

2010

dbSNP:

rs17190134

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0042900
Disease:

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010

dbSNP:

rs2428514

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs2523849

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs2523849

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs4713429

Entrez Id:	285834
Gene Symbol:	HCG22

HCG22

CUI:	C0026769
Disease:

Multiple Sclerosis

0.700

GeneticVariation

GWASDB

Risk alleles for multiple sclerosis identified by a genomewide study.

17660530

2007