XKR6, XK related 6, 286046

N. diseases: 25; N. variants: 20
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4841465
rs4841465
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs6982751
rs6982751
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
dbSNP: rs12546366
rs12546366
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0424621
Disease:
Body Fat Distribution 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. 30664634 2019
dbSNP: rs4841504
rs4841504
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0010054
Disease:
Coronary Arteriosclerosis 		0.010 GeneticVariation BEFREE Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke. 31429711 2019
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE These data revealed that the XKR6 rs7819412 A allele was related to increased serum TG levels in CAD, TC levels in ischemic stroke patients and high risk of CAD and ischemic stroke. 31429711 2019
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0010068
Disease:
Coronary heart disease 		0.010 GeneticVariation BEFREE Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke. 31429711 2019
dbSNP: rs2898261
rs2898261
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0341106
Disease:
Eosinophilic esophagitis 		C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104 2014
dbSNP: rs10096421
rs10096421
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0017654
Disease:
Glomerular Filtration Rate 		T 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs11783418
rs11783418
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0017654
Disease:
Glomerular Filtration Rate 		A 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs6982751
rs6982751
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0018621
Disease:
Hay fever 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0948008
Disease:
Ischemic stroke 		0.010 GeneticVariation BEFREE These data revealed that the XKR6 rs7819412 A allele was related to increased serum TG levels in CAD, TC levels in ischemic stroke patients and high risk of CAD and ischemic stroke. 31429711 2019
dbSNP: rs7460469
rs7460469
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.710 GeneticVariation GWASCAT In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans. 29967481 2018
dbSNP: rs7460469
rs7460469
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.710 GeneticVariation BEFREE In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans. 29967481 2018
dbSNP: rs11783247
rs11783247
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs12548184
rs12548184
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017
dbSNP: rs4240671
rs4240671
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs6984496
rs6984496
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs6985109
rs6985109
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs35792458
rs35792458
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1269683
Disease:
Major Depressive Disorder 		C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929 2018
dbSNP: rs9969436
rs9969436
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0428886
Disease:
Mean blood pressure 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE We tested for gene-gene interactions between TaqIB SNP in the cholesterol ester transfer protein (CETP) and three novel single nucleotide polymorphisms (SNPs), namely rs11774572, rs7819412 and rs6995374 for their effect on metabolic syndrome (MetS) components and related traits. 19364639 2010
dbSNP: rs17152930
rs17152930
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.700 GeneticVariation GWASDB The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations. 21866343 2012
dbSNP: rs35792458
rs35792458
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C3158111
Disease:
response to SSRI 		C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929 2018
dbSNP: rs149776388
rs149776388
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of paliperidone efficacy. 27846195 2017