XKR6, XK related 6, 286046

N. diseases: 25; N. variants: 20
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0202236
Disease:
Triglycerides measurement 		G 0.800 GeneticVariation GWASDB Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
dbSNP: rs7819412
rs7819412
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0202236
Disease:
Triglycerides measurement 		G 0.800 GeneticVariation GWASCAT Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
dbSNP: rs7460469
rs7460469
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.710 GeneticVariation GWASCAT In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans. 29967481 2018
dbSNP: rs7460469
rs7460469
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.710 GeneticVariation BEFREE In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans. 29967481 2018
dbSNP: rs10096421
rs10096421
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0017654
Disease:
Glomerular Filtration Rate 		T 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs11779675
rs11779675
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0037369
Disease:
Smoking 		A 0.700 GeneticVariation GWASCAT Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. 30643258 2019
dbSNP: rs11783418
rs11783418
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0017654
Disease:
Glomerular Filtration Rate 		A 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs12546366
rs12546366
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0424621
Disease:
Body Fat Distribution 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. 30664634 2019
dbSNP: rs4841504
rs4841504
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs35792458
rs35792458
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0041696
Disease:
Unipolar Depression 		C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929 2018
dbSNP: rs35792458
rs35792458
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1269683
Disease:
Major Depressive Disorder 		C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929 2018
dbSNP: rs35792458
rs35792458
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C3158111
Disease:
response to SSRI 		C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929 2018
dbSNP: rs4841465
rs4841465
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs4841465
rs4841465
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs4841465
rs4841465
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C1306620
Disease:
Systolic blood pressure measurement 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs9969436
rs9969436
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0428886
Disease:
Mean blood pressure 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs10107145
rs10107145
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0871470
Disease:
Systolic Pressure 		G 0.700 GeneticVariation GWASCAT Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. 28739976 2017
dbSNP: rs12548184
rs12548184
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017
dbSNP: rs149776388
rs149776388
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of paliperidone efficacy. 27846195 2017
dbSNP: rs2898261
rs2898261
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0341106
Disease:
Eosinophilic esophagitis 		C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104 2014
dbSNP: rs6982751
rs6982751
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0018621
Disease:
Hay fever 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
dbSNP: rs6982751
rs6982751
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
dbSNP: rs17152930
rs17152930
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.700 GeneticVariation GWASDB The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations. 21866343 2012
dbSNP: rs11783247
rs11783247
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs4240671
rs4240671
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008