GPX1, glutathione peroxidase 1, 2876

N. diseases: 290; N. variants: 12
Disease: Hypertensive disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1050450
rs1050450
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0020538
Disease:
Hypertensive disease 		0.020 GeneticVariation BEFREE This study examined the SNPs AGT rs699 (Met235Thr), ADD1 rs4961 (Gly460Trp), NPPA rs5063 (Val32Met), GPX1 rs1050450 (Pro198Leu), and AGTR1 rs5186 (A1166C) in relation to hypertension and salt sensitivity. 27480094 2017
dbSNP: rs1050450
rs1050450
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0020538
Disease:
Hypertensive disease 		0.020 GeneticVariation BEFREE Univariate analysis failed to demonstrate an association between either the -262C/T of the catalase gene promoter (rs1001179) or the C242T polymorphism of the P22phox gene (rs4673) or the 594C/T polymorphism of the glutathione peroxidase gene (rs1050450) and AH. 23701472 2014
dbSNP: rs1043210477
rs1043210477
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília. 21053180 2010