GRM5, glutamate metabotropic receptor 5, 2915

N. diseases: 189; N. variants: 37
Disease: Schizophrenia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3824927
rs3824927
Entrez Id: 2915;100873989
Gene Symbol: GRM5;GRM5-AS1
GRM5;GRM5-AS1
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE For rs3824927, compared to major allele homozygotes, minor allele carriers with schizophrenia had lower Intelligence Quotients (IQ). 28405888 2018
dbSNP: rs60954128
rs60954128
Entrez Id: 2915;100873989
Gene Symbol: GRM5;GRM5-AS1
GRM5;GRM5-AS1
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Schizophrenia minor allele carriers of rs60954128 had reduced right hippocampal volume relative to healthy controls of the same genotype (-12.3%); this effect was exaggerated in males with schizophrenia (-15.6%). 28405888 2018