GRM6, glutamate metabotropic receptor 6, 2916

N. diseases: 28; N. variants: 16
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11746675
rs11746675
Entrez Id: 2916
Gene Symbol: GRM6
GRM6
CUI: C0271183
Disease:
Severe myopia
0.010 GeneticVariation BEFREE The genetic model analysis found that GRM6-rs11746675 and GRM6-rs2067011 were suggestively associated with high myopia in the recessive model (OR=0.54, P=0.004; OR=0.52, P=0.003; respectively). 27034204 2016
dbSNP: rs2067011
rs2067011
Entrez Id: 2916
Gene Symbol: GRM6
GRM6
CUI: C0271183
Disease:
Severe myopia
0.010 GeneticVariation BEFREE Haplotype GAT for GRM6 markers rs2067011-rs2645339-rs762724 showed significance (P=0.0239), but such association did not remain significant after multiple testing corrections.ConclusionsOur data suggested that genetic variants in GRM6 are associated with high myopia. 27034204 2016
dbSNP: rs2645339
rs2645339
Entrez Id: 2916
Gene Symbol: GRM6
GRM6
CUI: C0271183
Disease:
Severe myopia
0.010 GeneticVariation BEFREE Haplotype GAT for GRM6 markers rs2067011-rs2645339-rs762724 showed significance (P=0.0239), but such association did not remain significant after multiple testing corrections.ConclusionsOur data suggested that genetic variants in GRM6 are associated with high myopia. 27034204 2016
dbSNP: rs762724
rs762724
Entrez Id: 2916
Gene Symbol: GRM6
GRM6
CUI: C0271183
Disease:
Severe myopia
0.010 GeneticVariation BEFREE Haplotype GAT for GRM6 markers rs2067011-rs2645339-rs762724 showed significance (P=0.0239), but such association did not remain significant after multiple testing corrections.ConclusionsOur data suggested that genetic variants in GRM6 are associated with high myopia. 27034204 2016