GSK3B, glycogen synthase kinase 3 beta, 2932

N. diseases: 393; N. variants: 25
Disease: Depressive disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs334558
rs334558
Entrez Id: 2932;107986119
Gene Symbol: GSK3B;LOC107986119
GSK3B;LOC107986119
CUI: C0011581
Disease:
Depressive disorder 		0.020 GeneticVariation BEFREE The association of a depressive disorder and remission rates with polymorphisms rs334558 in the <i>GSK3B</i> gene and rs1130214 and rs3730358 in the <i>AKT1</i> gene was evaluated with a chi-square test. 30050316 2018
dbSNP: rs334558
rs334558
Entrez Id: 2932;107986119
Gene Symbol: GSK3B;LOC107986119
GSK3B;LOC107986119
CUI: C0011581
Disease:
Depressive disorder 		0.020 GeneticVariation BEFREE We observed a triple interaction of 5-HTTLPR, rs334558 and treatment on severity of depression. 22119086 2012
dbSNP: rs12630592
rs12630592
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease:
Depressive disorder 		0.010 GeneticVariation BEFREE In mood disorder patients, the level of mania (in both acute and stabilized periods) and depression in stabilized periods was positively associated with GSK3B rs12630592 T only in FXR1 rs496250 A-allele carriers (Bonferroni-corrected interaction p=0.024, 0.052 and 0.017 respectively). 28242499 2017